Khyber's History
Five years prior to Omniverse
Khyber was hired by Malware and Dr. Psychobos to get Ben's Omnitrix so that they could reverse engineer it to build a device of "superior" quality. They paid him with their device based on the Omnitrix, the Nemetrix. Khyber spent an amount of time afterwards collecting the DNA of the most fierce and savage of the universe's predators and added their DNA to the Nemetrix.
Khyber also collected a number of "volunteers" from the Null Void, such as Phil Billings, to test out the Nemetrix. Nearly all the tests failed miserably, learning that only a non-sapient creature could operate the Nemetrix without suffering from severe side effects since "higher functioning" creatures can't handle the savage nature of the predators, ultimately attaching it to his dog, an Anubian Baskurr. Originally, he was later tasked to obtain DNA samples from Ben's Omnitrix to complete the Nemetrix.
Omniverse
Khyber first appeared in The More Things Change: Part 1, where he spotted Ben investigating the wreckage of Pakmar's destroyed "toilet store" and sent his dog to attack Ben as Crabdozer. Once Crabdozer had Spidermonkey pinned down, Khyber recalls her, observing that Ben was "worthy prey".
In The More Things Change: Part 2, Khyber sent his dog after Ben again but this time as Buglizard. When Rook saved Ben, Khyber called Buglizard back until he could get Ben alone. Khyber got his chance to attack Ben when he was alone during his fight against Psyphon, sending Buglizard after him again but this time, Ben was able to defeat Buglizard as Shocksquatch. Later back at his ship, Khyber decided that Ben is more resourceful and skillful than he thought.
Later, Khyber stealthily broke into Plumber HQ to steal information on his employer Malware as well as the Helix, watching a video depicting the events of Trouble Helix, the first fight between Ben and Malware. Once the video was over, Khyber copied all files relating to the Helix, as well as files on Ben and Malware and left.
During the events of It Was Them, Khyber sent his pet after Ben first at Burger Shack as Slamworm, whom Ben was able to defeat as Diamondhead. Later Khyber sent his pet after Ben a second time at Dr. Animo's ant hill, where he had nearly defeated Crashhopper as Mucilator before Rook saved Ben. Ben defeated Mucilator by freeing Animo's Mutant Ants from his control and letting them attack Mucilator, forcing her to flee. Khyber tells his pet to be patient, as next time, Animo won't be getting in their way.
In Of Predators and Prey: Part 1, Khyber spotted Rook and Ben apparently breaking off their partnership and takes the opportunity to attack Ben in person with Zed, successfully capturing Ben after a grueling battle between the two Omnitrix users.
In Of Predators and Prey: Part 2, Khyber brought Ben to his ship and explained to him his history with his old nemesis, Malware. Afterwards, he and Rath got into a short fight in which Khyber easily won using a simple nerve pinch. However, Rook arrived and saved Ben, revealing that their earlier break up was part of a elaborate ruse to lure Khyber and Zed out of hiding.
While Ben and Zed got into a fight, Rook fought Khyber, trying to get his hands on Khyber's whistle that he used to command Zed. After learning that Khyber is the whistle, Rook simply muzzled him, allowing Ben to defeat Tyrannopede as Grey Matter using the same neural pinch Khyber used on him and rescued Rook from the crashing ship as Big Chill. Though Khyber and Zed survived the crash, they were soon found by Malware and Dr. Psychobos.
In Outbreak, Khyber tried to keep Zed under control while the Nemetrix was malfunctioning but failed, with Zed continuing to randomly change form. According to Dr. Psychobos, the needed component to stabilize the Nemetrix was in the Omnitrix itself. Malware and Khyber argued over who would get the component, but Dr. Psychobos insisted that he did it himself.
In Malefactor, Khyber and Zed attacked Ben and Rook at the "Olde Bellwood Days" festival in order to keep them from discovering that Malware was stealing data files from the Plumber database from Rook's Proto-TRUK, until Ben discovered that it was a distraction at which point Khyber directed them towards Rook's truck for his own reasons before he and Zed retreated.
In Showdown: Part 1, Khyber is seen with Dr. Psychobos, who plans to take down Azmuth and the entire Galvan race using their own predator: Omnivoracious. He and Dr. Psychobos use Zed to transform into an Omnivoracious and they corner Azmuth. Azmuth quickly transports Ben and Rook to his side and Khyber quickly wants to fight Ben.
Khyber orders Zed to attack Ben, but Dr. Psychobos uses his electrical powers to force Khyber to whistle, causing Zed to transform back into an Omnivoracious to attack Azmuth. Once Azmuth creates a flute that sounds exactly like Khyber's whistle, Khyber turns on Dr. Psychobos, allowing Azmuth to turn Omnivoracious into Dr. Psychobos' own natural predator: Vicetopus.
Vicetopus traps Dr. Psychobos, allowing Ben, Rook, and Azmuth to take him away. Smoke then engulfs the area and the Nemetrix is suddenly gone from Zed's collar. It is revealed that Khyber has made off with the Nemetrix and abandoned Zed.
In The Ultimate Heist, Khyber returns and forms a alliance with Albedo. While Ben was on mess duty, he broke into Plumber's HQ and, after a few cosmetic changes to Ben, switched him with Albedo. Later on after Albedo completed the new Ultimatrix, Khyber rescued him after his defeat by Argit.
In A Fistful of Brains, after Albedo captured Ben, Albedo dropped him in Khyber's hunting preserve, where he introduced his newest pet, a Panuncian.
In For a Few Brains More, Ben and his friends were able to escape his HQ, causing it to self-destruct. After chasing them to Earth, he and his Panuncian fought Ben, Rook, Gwen and Kevin, but he was ultimately defeated and revealed that he had a fear of Nemuinas when Ben transformed into Pesky Dust. After putting Khyber to sleep and gaining information from his dreams, he and his pet were left for the Plumbers to pick up, but they escaped before the Plumbers could reach them.
In Stuck on You, he steals the Nemetrix from within Plumber Headquarters, leaving a mocking remark to Ben for the security cameras. He then travels to the Black Hole, and approaches Trumbipulor, revealing that he has a Slimebiote named Skurd on him. Khyber offers Skurd the opportunity to feed on the Nemetrix's DNA in exchange for a partnership, to which Skurd agrees.
Khyber and Skurd find and attack Ben, Khyber using Skurd's powers to grant him the abilities of Crabdozer. Ben is teleported away before they can finish him. Ben later teleports onto Khyber's ship. Skurd, realizing that the Omnitrix has far more DNA to feed on then the Nemetrix, abandons Khyber for Ben, turning Khyber into Tyrannopede in the process. Giving in to the predator's savage nature, Khyber attacks Ben. Ben and Skurd work together to distract Khyber long enough for Rook to remove the Nemetrix, reverting him back to normal. Khyber is then taken into Plumber custody.
